This study investigated the effects of Walnut kernel powder (WP) and Jacobinia leaf powder (JP) dietary supplementation on the performance, blood, and antioxidant status of broiler chickens administered aflatoxin B (AF) 1 contaminated diets. 200 day-old broiler chicks were randomly assigned to four diets (50 birds/treatment; 10 birds/replicate): CONT: No contamination/ supplementation; AFNS: 0.5 mg/kg AF; AFWP: 0.5 mg/kg AF +350 mg/kg WP; AFJP: 0.5 mg/kg AF+350 mg/kg JP. The final weight and weight gain of the birds in AFNS were significantly (P0.05). The total feed intake (FI) and feed conversion ratio (FCR) of the broiler birds fed AFNS were significantly (P<0.05) lower than those fed CONT, AFWP, and AFJP. The Dressed percentage of the birds fed AFNS reduced significantly (P<0.05), compared to those birds fed CONT, AFWP, and AFJP. The relative weights of liver, spleen and pancreas of the birds fed AFNS were significantly (P<0.05) affected by AFB . The RBC, HbC and PCV of the birds fed AFNS were 1 significantly (P<0.05) lower compared to the birds fed the rest diets. The serum GPx and CAT concentrations were lower (P<0.05) in birds fed AFNS compared to those fed the control, AFWP, and AFJP. The LDH of the birds fed AFNS were higher (P<0.05) than those fed the rest diets. 350 mg/kg of WP and JP as dietary supplements is recommended in broiler chicken diets that are exposed to dietary AFB contamination.