This study assessed the impact of incorporating maggot meal diets at varied inclusion levels on the growth and health parameters of Clarias gariepinus. After a 14-day acclimatization period, a total of 225 juvenile fish were randomly assigned to 5 experimental groups with each group replicated 3 times (15 fish per replicate). Over an 84-day period, fish groups were fed diets containing varied levels of maggot meal: 0 (control), 25, 50, 75, and 100% in replacement for fish meal. Weight gain and specific growth rate (SGR) were determined, and blood samples were analyzed at the end of the experiment. Significant differences (p<0.05) were observed in final mean weight gain, with the highest gain at 50% maggot meal (49.77±9.16g) and the lowest at 100% (30.77±5.87g). Specific growth rate varied significantly (p<0.05), with lowest at 100% replacement level (2.42±0.36%/day) and highest at the 50% replacement level (3.22±0.36%/day). Packed cell volume was significantly higher at 25% inclusion (42.0±0.4%), and haemoglobin concentration were significantly similar at 25% (14.0±0.6g/dL) and 50% (12.7±0.5g/dL) replacement levels. Significant differences (p<0.05) of serum biochemical values emerged across replacement levels. In conclusion, maggot meal inclusion up to 50% improved growth performance without compromising fish health, suggesting its potential in juvenile fish aquaculture.